i~HD (www.i-hd.eu) is an international not for profit institute registered in Belgium. It is a membership-based organisation with members from pharma, healthcare providers, academic organisations, and works closely with patient organisations, healthcare payers, the health ICT sector and standards development organisations. i~HD develops methods, solutions and services that can maximise multi-stakeholder value obtained from health data, to support innovations in health, health care and knowledge discovery, while ensuring compliance with privacy protection. It tackles areas of challenge in the successful scaling up of innovations that rely on high quality and interoperable health data. It collates, develops and supports adoption of best practices in information governance and data protection. Its activities include a Network of Excellence for healthcare providers, data quality assessment and improvement support, promoting codes of practice and expertise in sustainability and business modelling. i~HD has staff with experience of leading or being a partner in over 80 EC projects.