King’s College London is one of the top 20 universities in the world and the fourth oldest university in England. KCL is a research-led university based in the heart of London, and currently involved in c.200 European Commission projects.

The Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s is Europe’s largest centre for research in these fields with the highest combined citations outside the US and second highest research power for Psychology, Psychiatry and Neuroscience nationally. The global Highly Cited Researchers list includes 21 researchers from the IoPPN [Clarivate Analytics Highly Cited Researchers list, 2018].

A key strength of the IoPPN is the close association between academic and clinical disciplines and in partnership we host the National Institute for Health Research (NIHR) Biomedical Research Centre (BRC), with a research theme in depression that is led by Professor Pariante (see below) and has a particular focus on clinical trials in TRD.

In relation to EU-PEARL, KCL has expertise in:

– Clinical networks and RWD, and especially: on developing clinical networks and networks of patient-level data (EHRs); the use of clinical databases and patient registries; sharing of information related to clinical trials and data standards; leadership of and access to clinical site consortia and networks in the disease areas

– Specific Expertise Extensive in major depressive disorder (MDD)

The research portfolio of KCL, the IoPPN and the associated BRC comprises neurobiology, mechanistic studies, informatics and modelling, alongside clinical trials informed by novel biomarkers and new therapeutic targets.

Professor Pariante leads many such initiatives in the context of TRD. In addition, the IoPPN has a tradition of successful public engagement, and Professor Pariante has a very strong presence on the media for disseminating knowledge about depression and antidepressants.

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