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The core of the EU-PEARL initiative is to revolutionise the way clinical trials are conducted by making them more efficient and patient friendly through allowing multiple intervention developers to test their candidate drugs simultaneously against a shared placebo group. The conclusion of EU PEARL will see sustainable and reusable Integrated Research Platforms (IRPs) in place...
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EU-PEARL will present the latest advancements made on the statistical and methodological side of the IRP solution during the upcoming PSI (Statisticians in the Pharmaceutical Industry) 2021 Conference .The event will take place between 21st and 23rd of June in a virtual format. The PSI conference is an important annual event for statisticians in the...
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Britt Dhaenens, MD and PhD student at Erasmus University Medical Center (The Netherlands) shares in this interview her amazing journey from patient to researcher. She tells us about her experience in EU-PEARL; the challenges she is contributing to address and the implications for rare diseases patients.  What ignited your scientific vocation? I have been interested...
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On occasion of International Clinical Trial Day (ICTD) we have asked Dr. Burç Aydin, Project Manager at ECRIN and EU-PEARL member, to share his views on the challenges and new opportunities platform trials entail for the future of clinical research. What is the purpose of the ECRIN International Clinical Trials Day? ECRIN launched International Clinical...
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Next May 20th is International Clinical Trials Day (ICTD). EU-PEARL will actively participate in the event organised every year by ECRIN, a partner in the Consortium, to foster debate around multinational clinical trials. This edition, ICTD will focus on platform trials, a topic at the heart of EU-PEARL. Indeed, this IMI project is creating a...
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An overview of our first scientific meeting by Courtney Worrell At the beginning of 2020, myself and the WP4 team were hopeful that in May of that same year we would all come together in central London, joined by some of the most prevalent figures in MDD research. Sadly, COVID-19 had other plans for us,...
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18 April 2021 marks the celebration of the 15th Patients’ Rights Day. Patients’ Rights Day is held every year to support the official recognition of this important day across Europe. This year, Patients’ Rights Day will be celebrated in a two day conference focusing on the role of civic society and patient advocacy groups for...
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On occasion of World TB Day, we talk to EU-PEARL specialists on Tuberculosis (TB) Daniella Maria Cirillo and Riccardo Alagna to learn about where we are in the fight against TB, what is needed to meet UN targets for 2030 and how this IMI project is contributing to it.   Today is World TB day....
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The COVID-19 pandemic has created renewed appreciation for the tremendous impact healthcare and pharmaceutical innovation has on the health and daily lives of society. Public-private partnerships to develop vaccines and therapeutics in response to the pandemic have significantly raised public awareness about clinical trials and global clinical trial infrastructure. Established clinical development paradigms in which...
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Non-alcoholic fatty liver disease (NAFLD) is defined as the buildup of fat in the liver. Its more advanced form, non-alcoholic steatohepatitis (NASH), is characterized by inflammation and damage to liver cells, which can lead to tissue scarring or fibrosis. These are silent diseases where patients initially have few or no symptoms, hampering early detection. However,...
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