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Paris NASH Meeting 2022 has distinguished EU-PEARL’s poster presentation “Boosting drug development in NASH through integrated research platforms: proposal of a master protocol for a NASH platform trial” with the Best Poster Presentation Award. Paris NASH is an important international scientific conference which brings together key opinion leaders in the field of NASH (Nonalcoholic steatohepatitis)....
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Depression, is a serious and potentially life-threatening condition affecting up to 1 in 6 adults at some point during their lifetime. While considerable efforts over the past 40 years have led to the introduction of safer and better tolerated pharmacological treatments, they only achieve sufficient symptom reductions in about 50% of the patients with this...
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EU-PEARL will present the poster “Boosting drug development in NASH through integrated research platforms: proposal of a master protocol for a NASH platform trial” during the Paris NASH Meeting next 8th-9th of September. This is an important international scientific conference which takes place annually at Institut Pasteur in Paris and brings together key opinion leaders...
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EU-PEARL advances to design a platform trial for Tuberculosis (TB) will open the 42nd Annual Meeting of the European Society of Mycobacteriology due to take place next 26-29th of June in Bologna (Italy). Francesca Saluzzo, from Vita-Salute San Raffaele University and a researcher in EU-PEAR will offer the oral presentation: “Looking for early treatment response...
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18th Conference of the Spanish Section of the International Biometric Society, organized by the Carlos III University of Madrid and Rey Juan Carlos University, was held from 25 to 27 May in Madrid, Spain. EU-PEARL researchers Marta Bofill Roig and Pavla Krotka participated with two oral presentations in contributed sessions. Pavla Krotka presented the extended...
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NASH Platform trial
Vall d’Hebron Institute of Research (VHIR) and the Liver Unit of Vall d’Hebron University Hospital (VHUH) hosted a scientific meeting in Barcelona last May 11th & 12th to discuss the next steps in the development of platform trials for Non-Alcoholic Steatohepatitis (NASH) disease. The meeting brought together academic and industry experts closely collaborating in EU-PEARL...
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Platform Trials
By Sarai Rodríguez Navarro and Joan Genescà (VHIR) EU-PEARL (European Union-Patient-cEntric clinicAl tRial pLatforms), an IMI (Innovative Medicines Initiative)-founded project,  was conceived as a means to change the paradigm of clinical trials in Europe, by promoting more adaptive, efficient and patient-centered clinical trials, thus contributing to accelerate drug development and the access to new and...
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EU-PEARL is developing methodologies and tools to enable the scale-up of platform trials across Europe, and potentially worldwide. These include innovative Information and Communication Technology (ICT) methods and platform specifications to support platform trial queries using federated hospital real-world data. In this article, the authors describe the tools being developed and how these will pave...
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Luca Sforzini is M.D., Psychiatrist, Ph.D. student at Stress, Psychiatry & Immunology (SPI) Lab, Institute of Psychiatry, Psychology and Neuroscience, King’s College London (UK). As an early career investigator, he shares in this interview his views on mental health research and  his experience at EU-PEARL.     What started your scientific vocation? I have always been...
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  By members of EU-PEARL Patient Advisory Group (PAG) Claas Röhl,  Livia Alimena and Fiona Greenhalgh, and Juan Espinosa, member of the Expert Advisory Group (EAG). Patient and community engagement in R&D is essential to understand the needs of patients and tailor clinical trials accordingly. While patient engagement is on the rise, we still see...
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