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The 43rd Annual Conference of the International Society for Clinical Biostatistics (ISCB) will be held next 21-25 August 2022, in Newcastle upon Tyne, UK. The event aims to continue stimulating investigation in the design and analysis of clinical research and increase the relevance of statistics to the world of clinical medicine. Efficient clinical trial designs...
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EU-PEARL will actively participate in DIA Global 2022 which will be held in Chicago next 19-23 June. This important event for the life-sciences sector brings together representatives from industry, regulatory bodies, academia and patients to discuss scientific and medical innovations. Project representatives will intervene during the session Statistical issues in “Master Protocols: Beyond Type I...
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Vall d’Hebron Institute of Research (VHIR) and the Liver Unit of Vall d’Hebron University Hospital hosted a scientific meeting in Barcelona last May 11th & 12th to discuss the next steps in the development of platform trials for Non-Alcoholic Steatohepatitis (NASH) disease. The meeting brought together academic and industry experts closely collaborating in EU-PEARL to...
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By Sarai Rodríguez Navarro and Joan Genescà (VHIR) EU-PEARL (European Union-Patient-cEntric clinicAl tRial pLatforms), an IMI (Innovative Medicines Initiative)-founded project,  was conceived as a means to change the paradigm of clinical trials in Europe, by promoting more adaptive, efficient and patient-centered clinical trials, thus contributing to accelerate drug development and the access to new and...
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EU-PEARL is developing methodologies and tools to enable the scale-up of platform trials across Europe, and potentially worldwide. These include innovative Information and Communication Technology (ICT) methods and platform specifications to support platform trial queries using federated hospital real-world data. In this article, the authors describe the tools being developed and how these will pave...
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Luca Sforzini is M.D., Psychiatrist, Ph.D. student at Stress, Psychiatry & Immunology (SPI) Lab, Institute of Psychiatry, Psychology and Neuroscience, King’s College London (UK). As an early career investigator, he shares in this interview his views on mental health research and  his experience at EU-PEARL.     What started your scientific vocation? I have always been...
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DIA EUROPE 2022 is to take place next 29-31 March in a hybrid format -in Brussels and online- under the title “Advancing Health Priorities”. EU-PEARL Consortium member Francesco Patalano (Novartis) will speak during the session “Accelerating Complex Innovative Clinical Trial Designs in Europe and Beyond” scheduled for Tuesday 29th to explain the progress made by the...
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Title:  To use, or not to use, non-concurrent controls? “When and how to use” – these are the questions! Date: February 24, 2022. 4pm to 7pm CET EU-PEARL  organized a webinar to discuss multi-stakeholder perspectives on challenges and opportunities for the use of non-concurrent control data in platform trials. Augmenting control groups with non-concurrent controls can...
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  By members of EU-PEARL Patient Advisory Group (PAG) Claas Röhl,  Livia Alimena and Fiona Greenhalgh, and Juan Espinosa, member of the Expert Advisory Group (EAG). Patient and community engagement in R&D is essential to understand the needs of patients and tailor clinical trials accordingly. While patient engagement is on the rise, we still see...
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  When and what started your scientific vocation? I have always been a curious person and have been fascinated by science. But it was when I started my master’s degree in statistics that I became interested in research, particularly in statistics applied to medicine. This combines actual challenges in health with the need to adapt...
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